Dukkha

[Pali “out-of-alignment”] Variously translated as suffering, pain, sorrow, discontent, imperfection, sin, evil. In Buddhist doctrine, dukkha is one of the three characteristics of existence—along with anicca, impermanence, or transience, and anatta, non-separateness (having no separate soul or ego; no exclusive possession of the immortal spirit).

Sources

Pearls of Wisdom, vol. 29, no. 77.